Genetic variants within the endothelin-1 gene (EDN1) have been associated with several cardiovascular diseases and may act as genetic prognostic markers.Here, we explored the overall relevance of EDN1 polymorphisms for long-term survival in patients undergoing on-pump cardiac surgery.A prospectively collected cohort of 455 Caucasian patients who un
Summary: Mass cytometry by time-of-flight (CyTOF) is an emerging technology allowing for in-depth characterization of cellular heterogeneity in cancer and other diseases.Unfortunately, high-dimensional analyses of CyTOF data remain quite demanding.Here, we deploy a bioinformatics framework that tackles two fundamental problems in CyTOF analyses nam
Abstract High-dimensional linear regression model is the most popular statistical model for high-dimensional data, but it is quite a challenging task First Aid to achieve a sparse set of regression coefficients.In this paper, we propose a simple heuristic algorithm to construct sparse high-dimensional linear regression models, which is adapted from
Various environmental, food security and population health problems have been correlated Shroud Right with the use of intensive agriculture production systems around the world.This type of system leads to the loss of biodiversity and natural habitats, high usage rates of agrochemicals and natural resources, and affects soil composition, human healt
Objective To explore the risk factors for restless legs syndromes (RLS) in patients with ischemic cerebrovascular disease (ICVD).Methods There were 370 patients with ICVD, 45 cases were combined with RLS (RLS group) and 325 cases were not combined with RLS (non-RLS group).The general clinical data [sex, age, body mass index (BMI), education, nation